NovAliX technologies

Focusing on biophysical sciences

NovAliX strongly believes in biophysical sciences for investigation and characterization of small molecules and biologics and has continously invested in the development of corresponding capabilities to support progress in research and development programs.

X-Ray Cristallography NovAliX structural biology group is a world leader in the nuclear hormone receptors field and have extended its expertise to numerous protein classes including kinases, proteases, phosphotases, PDEs or protein/antibody complexes by using an efficient gene-to-structure platform combined with strong know-how in crystallography.	NMR NovAliX NMR group provides expertise and proprietary solutions leveraging the three major NMR technologies Solution-phase for screening and complex mixture analysis (DOSY experiment) Solid-state for polymorphism and formulation studies HR-MAS for soft-solid, emulsion and gel characterization
Native MS NovAliX has developed a unique and innovative platform using supramolecular mass spectrometry for compound screening and binding characterization. This screening technology has emerged as a novel and efficient technique for delivering high-content information on compound-protein interactions. Vivat et al., Future Med. Chem., Jan 2010 (2), 1, 35-50.	SPR The Graffinity technology is a unique platform which includes chemical microarrays with a proprietary SPR label-free imaging system for characterization of protein-ligand as well as protein--protein interactions. It's high sensitivity and throughput makes it the technology of choice for fragment screening. Neumann et al., Curr Top Med Chem. 2007;7(16):1630-42.

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