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March 8, 2017

Discovery of phenoxyindazoles and phenylthioindazoles as ROR gamma inverse agonists

Gilles Ouvry, Claire Bouix-Peter, Fabrice Ciesielski, Laurent Chantalat, Olivier Christin, Catherine Comino, Denis Duvert, Christophe Feret, Craig S. Harris, Laurent Lamy, Anne-Pascale Luzy, Branislav Musicki, Danielle Orfila, Jonathan Pascau, Véronique Parnet, Agnès Perrin, Romain Pierre, Gaëlle Polge, Catherine Raffin, Yves Rival, Nathalie Taquet, Etienne Thoreau, Laurent F. Hennequin

Bioorganic & Medicinal Chemistry Letters 26 (2016) 5802–5808; http://dx.doi.org/10.1016/j.bmcl.2016.10.023

October 26, 2015

Identification of Small Molecule Inhibitors of Tau Aggregation by Targeting Monomeric Tau As a Potential Therapeutic Approach for Tauopathies

Marcus Pickhardt, Thomas Neumann, Daniel Schwizer, Kari Callaway, Michele Vendruscolo, Dale Schenk, Peter St. George-Hyslop, Eva M. Mandelkow, Christopher M. Dobson, Lisa McConlogue, Eckhard Mandelkow and Gergely Toth.

Current Alzheimer Research, 2015, 12(9), 814-828