Structural studies

Target based drug discovery is highly dependent upon models using structures of apo proteins and ligand-target co-crystals determined by X-ray crystallography. This in turn relies upon skills in protein construct design, protein expression and purification and then the exploration of a large number of conditions to favor crystallization.

There is no substitute for years of experience in all of these activities. The structural determination platform is performed according to workflows that have been refined over many years and thereby achieves highly cost effective and reliable services.